Free Bradford Assay Calculator

Calculate protein concentration from Bradford assay absorbance using a linear calibration curve.

Protein Concentration

8.60 ug/mL

Protein Concentration0.0086 mg/mL

Protein Concentration vs Absorbance at 595 nm

Bradford Protein Assay

The Bradford assay uses Coomassie Brilliant Blue G-250 dye, which shifts from red to blue upon binding protein. Absorbance at 595 nm is proportional to protein concentration.

Calculation

[Protein] = (A595 - b) / m × dilution factor

where m and b come from a standard curve using BSA or another reference protein. The Bradford assay is sensitive to 1-20 ug/mL but has protein-to-protein variation.

Example Calculation

A Bradford assay reads A595 = 0.45, standard curve: m = 0.05, b = 0.02, no dilution.

  1. 01[Protein] = (0.45 - 0.02) / 0.05 × 1
  2. 02[Protein] = 0.43 / 0.05 = 8.60 ug/mL

Frequently Asked Questions

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