Free Anion Gap Calculator

Calculate the serum anion gap from basic metabolic panel values to help identify metabolic acidosis causes.

mEq/L
mEq/L
mEq/L
g/dL

Anion Gap

12 mEq/L

Albumin-Corrected AG12.0 mEq/L
Delta Ratio (if AG elevated)

Anion Gap vs Sodium (Na+)

Anion Gap Formula

AG = Na+ - Cl- - HCO3-

Normal Range

Normal anion gap: 8-12 mEq/L (without potassium)

Albumin Correction

Corrected AG = AG + 2.5 x (4.0 - Albumin)

Low albumin can mask an elevated anion gap.

Common Causes of Elevated Anion Gap (MUDPILES)

Methanol, Uremia, Diabetic ketoacidosis, Propylene glycol, Iron/Isoniazid, Lactic acidosis, Ethylene glycol, Salicylates

Example Calculation

Na 140, Cl 104, HCO3 24, Albumin 4.0.

  1. 01AG = 140 - 104 - 24 = 12 mEq/L
  2. 02Corrected AG = 12 + 2.5 x (4.0 - 4.0) = 12
  3. 03Normal anion gap (8-12)

Frequently Asked Questions

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