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mg/dL
g/dL

Corrected Calcium

9.3 mg/dL

Adjustment Amount0.8 mg/dL

Corrected Calcium vs Total Serum Calcium

公式

Corrected Calcium Formula

Corrected Ca = Total Ca + 0.8 x (4.0 - Albumin)

About 40% of serum calcium is bound to albumin. When albumin is low, total calcium appears low even if ionized (active) calcium is normal.

Normal Ranges

TestNormal Total Calcium8.5-10.5 mg/dL Albumin3.5-5.0 g/dL Corrected Ca8.5-10.5 mg/dL

计算示例

Total calcium 8.5 mg/dL with albumin 3.0 g/dL.

  1. 01Adjustment = 0.8 x (4.0 - 3.0) = 0.8 mg/dL
  2. 02Corrected Ca = 8.5 + 0.8 = 9.3 mg/dL
  3. 03Within normal range (8.5-10.5)

常见问题

Why do we correct calcium for albumin?

About 40% of calcium in the blood is bound to albumin. When albumin is low (common in hospitalized patients), total calcium underestimates the true calcium status.

When is corrected calcium needed?

Corrected calcium should be calculated whenever albumin is below 4.0 g/dL. This is common in liver disease, malnutrition, nephrotic syndrome, and critical illness.

What causes high corrected calcium?

Hyperparathyroidism, malignancy, vitamin D excess, thiazide diuretics, and granulomatous diseases are common causes of elevated calcium.

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